Actor Eric Dane, widely recognized for his role as Dr. Mark Sloane on Grey’s Anatomy, has revealed his diagnosis with ALS (amyotrophic lateral sclerosis), a progressive and fatal neurological disease. In a heartfelt interview with Diane Sawyer on Good Morning America, the 52-year-old shared how the disease began subtly with weakness in his right hand, which he initially dismissed. However, after several visits to specialists and neurologists, he received the life-altering diagnosis that marked the beginning of a difficult journey.
Facing Physical Decline, Dane Battles Fear, Loss, and the Pain of Uncertainty
Dane described the frightening progression of his condition, which has led to significant loss of function in his arms. Currently, he has one functioning arm, though he fears that even that mobility will soon deteriorate. Despite still being able to walk, Dane worries about losing use of his legs. The emotional impact of this steady physical decline is evident, especially as he shared the devastating memory of not being able to swim while on a boat trip with his daughter, Georgia—an activity he once excelled in as a competitive swimmer.

The diagnosis of ALS has been especially painful for Dane, who recalled the shock of hearing those three letters. He expressed deep sorrow and anger—not just for himself, but for the emotional toll it could take on his daughters, Billie and Georgia. Having lost his own father at a young age, he now faces the possibility of leaving his children too early, a reality he finds heartbreaking and unjust.
Continuing to Work, Cherishing Family, and Holding on to Hope Amid ALS Battle
Despite the challenges, Dane remains committed to continuing his work for as long as possible. He announced his diagnosis publicly in April and expressed gratitude for the support of his family and fans. He will return to the set of Euphoria while asking for privacy as he navigates this new phase of life. ALS is a degenerative disease with no cure, and while the average life expectancy after diagnosis is around three years, some patients live much longer.
Throughout the interview, Dane emphasized the importance of his family, particularly his wife Rebecca Gayheart, whom he called his “biggest champion.” While ALS presents enormous physical and emotional obstacles, Dane remains hopeful and determined. He doesn’t believe his story ends with this diagnosis and is choosing to focus on the time he has left, prioritizing moments with his loved ones and holding on to hope in the face of uncertainty.